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HRID1665309

反应详情

EQUATION

反应方程式

HRID 1665309 的结构方程式

REACTANTS

反应物

2
结构：O=S(=O)(Cl)c1c(Cl)nc2sccn12
HCID2799717

6-Chloroimidazo[2,1-b][1,3]thiazole-5-sulfonyl chloride

C5H2Cl2N2O2S2

结构：O=C1C(=O)c2ccccc2C2=C1SCC1(CCNCC1)O2
HCID57661820

Spiro[naphtho[1,2-b]-1,4-oxathiin-2(3H),4′-piperidine]-5,6-dione

C16H15NO3S

PRODUCTS

生成物

1
结构：O=C1C(=O)c2ccccc2C2=C1SCC1(CCN(S(=O)(=O)c3c(Cl)nc4sccn34)CC1)O2
HCID57661830

未命名化合物

PROCEDURE

实验过程

Compound 77 was synthesized using spiro[naphtho[1,2-b][1,4]oxathiine-2,4′-piperidine]-5,6-dione, 6-chloroimidazo[2,1-b][1,3]thiazole-5-sulfonyl chloride and conditions outlined in procedure P. M.p.=265-267° C.; 400 MHz 1H NMR (DMSO-d6) δ: 8.08-8.05 (m, 1H), 7.87-7.84 (m, 1H), 7.61-7.50 (m, 3H), 7.33-7.29 (m, 1H), 3.66-3.60 (m, 2H), 3.11 (s, 2H), 3.02-2.95 (m, 2H), 2.12-2.06 (m, 2H), 1.95-1.84 (m, 2H); LCMS: 522 [M+H].