2-(Bromomethyl)tetrahydro-2H-pyran → HCID 57661885, compound

Participants

Reaction Steps

Compound 119 was synthesized using spiro[naphtho[1,2-b][1,4]oxathiine-2,4′-piperidine]-5,6-dione, 2-(bromomethyl)tetrahydro-2H-pyran and conditions outlined in procedure V. M.p.=135-137° C.; 400 MHz 1H NMR (CDCl3) δ: 8.05 (d, 1H), 7.8 (d, 1H), 7.65 (t, 1H), 7.5 (t, 1H), 4.0 (d, 1H), 3.5 (dt, 2H), 2.9 (m, 3H), 2.65-2.3 (m, 4H), 2.1 (m, 2H), 1.9 (m, 3H), 1.5 (m, 4H), 1.3 (m, 2H); LCMS: 400 [M+H].

Provenance & Evidence