4-Bromo-1,1,1-trifluorobutane → HCID 57661910, compound

HRID 1665339Notes

Reaction equation

HRID 1665339 reaction equation
[NH:1]1[CH2:6][CH2:5][C:4]2([O:11][C:10]3[C:12]4[C:17]([C:18](=[O:21])[C:19](=[O:20])[C:9]=3[S:8][CH2:7]2)=[CH:16][CH:15]=[CH:14][CH:13]=4)[CH2:3][CH2:2]1.Br[CH2:23][CH2:24][CH2:25][C:26]([F:29])([F:28])[F:27]>>[F:27][C:26]([F:29])([F:28])[CH2:25][CH2:24][CH2:23][N:1]1[CH2:2][CH2:3][C:4]2([O:11][C:10]3[C:12]4[C:17]([C:18](=[O:21])[C:19](=[O:20])[C:9]=3[S:8][CH2:7]2)=[CH:16][CH:15]=[CH:14][CH:13]=4)[CH2:5][CH2:6]1

Participants

3

Reactant 2

HCID 5210064-Bromo-1,1,1-trifluorobutaneHCID 57661820Spiro[naphtho[1,2-b][1,4]oxathiine-2,4'-piperidine]-5,6-dione

Product 1

HCID 57661910HCID 57661910, compound

Procedure

Compound 141 was synthesized using spiro[naphtho[1,2-b][1,4]oxathiine-2,4′-piperidine]-5,6-dione, 4-bromo-1,1,1-trifluorobutane and conditions outlined in procedure V. LCMS: 412 [M+H]; Rt=0.96 min.

Sources & evidence

ORD record
ord-8176fc9ad55245eaab08b2e4bf2e0bd2
Source dataset
uspto-grants-2011_10
Patent number
US08039503B2

Reaction notes

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