1-(2-Bromoethoxy)-4-chlorobenzene → HCID 23654870, compound

HRID 1665343Notes

Reaction equation

HRID 1665343 reaction equation
[NH:1]1[CH2:6][CH2:5][C:4]2([O:11][C:10]3[C:12]4[C:17]([C:18](=[O:21])[C:19](=[O:20])[C:9]=3[S:8][CH2:7]2)=[CH:16][CH:15]=[CH:14][CH:13]=4)[CH2:3][CH2:2]1.Br[CH2:23][CH2:24][O:25][C:26]1[CH:31]=[CH:30][C:29]([Cl:32])=[CH:28][CH:27]=1>>[Cl:32][C:29]1[CH:30]=[CH:31][C:26]([O:25][CH2:24][CH2:23][N:1]2[CH2:2][CH2:3][C:4]3([O:11][C:10]4[C:12]5[C:17]([C:18](=[O:21])[C:19](=[O:20])[C:9]=4[S:8][CH2:7]3)=[CH:16][CH:15]=[CH:14][CH:13]=5)[CH2:5][CH2:6]2)=[CH:27][CH:28]=1

Participants

3

Reactant 2

HCID 748541-(2-Bromoethoxy)-4-chlorobenzeneHCID 57661820Spiro[naphtho[1,2-b][1,4]oxathiine-2,4'-piperidine]-5,6-dione

Product 1

HCID 23654870HCID 23654870, compound

Procedure

Compound 145 was synthesized using spiro[naphtho[1,2-b][1,4]oxathiine-2,4′-piperidine]-5,6-dione, 1-(2-bromoethoxy)-4-chlorobenzene and conditions outlined in procedure V. LCMS: 456 [M+H]; Rt=1.07 min.

Sources & evidence

ORD record
ord-7693bd64572e4b8bb04a8fc006b05981
Source dataset
uspto-grants-2011_10
Patent number
US08039503B2

Reaction notes

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