HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(2,2,2-Trifluoroethyl)oxirane → HCID 57662000, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(2,2,2-Trifluoroethyl)oxirane | HCID 2782635 | — |
| Reactant | Spiro[naphtho[1,2-b][1,4]oxathiine-2,4'-piperidine]-5,6-dione | HCID 57661820 | — |
| Product | HCID 57662000 | HCID 57662000 | — |
Reaction Steps
Compound 160 was synthesized using spiro[naphtho[1,2-b][1,4]oxathiine-2,4′-piperidine]-5,6-dione, 2-(2,2,2-trifluoroethyl)oxirane and conditions outlined in procedure X. M.p.=145-148° C.; 400 MHz 1H NMR (CDCl3) δ: 8.05 (d, 1H), 7.75 (d, 1H), 7.65 (t, 1H), 7.5 (t, 1H), 4.05 (m, 1H), 3.5 (s, 1H), 2.95 (m, 3H), 2.85-2.7 (m, 2H), 2.6-2.3 (m, 4H), 2.2-2.1 (m, 3H), 2.0-1.9 (m, 2H); LCMS: 428 [M+H].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08039503B2 |
| Source dataset | uspto-grants-2011_10 |
| ORD ID | ord-89a2f0dc5bb74973a39d1efeeab4923e |
| Source note | uspto-grants-2011_10 |