2-{[(Oxiran-2-yl)methoxy]methyl}furan → HCID 57661869, compound

HRID 1665362Notes

Reaction equation

HRID 1665362 reaction equation
[NH:1]1[CH2:6][CH2:5][C:4]2([O:11][C:10]3[C:12]4[C:17]([C:18](=[O:21])[C:19](=[O:20])[C:9]=3[S:8][CH2:7]2)=[CH:16][CH:15]=[CH:14][CH:13]=4)[CH2:3][CH2:2]1.[O:22]1[CH2:24][CH:23]1[CH2:25][O:26][CH2:27][C:28]1[O:29][CH:30]=[CH:31][CH:32]=1>>[O:29]1[CH:30]=[CH:31][CH:32]=[C:28]1[CH2:27][O:26][CH2:25][CH:23]([OH:22])[CH2:24][N:1]1[CH2:2][CH2:3][C:4]2([O:11][C:10]3[C:12]4[C:17]([C:18](=[O:21])[C:19](=[O:20])[C:9]=3[S:8][CH2:7]2)=[CH:16][CH:15]=[CH:14][CH:13]=4)[CH2:5][CH2:6]1

Participants

3

Reactant 2

HCID 943062-{[(Oxiran-2-yl)methoxy]methyl}furanHCID 57661820Spiro[naphtho[1,2-b][1,4]oxathiine-2,4'-piperidine]-5,6-dione

Product 1

HCID 57661869HCID 57661869, compound

Procedure

Compound 165 was synthesized using spiro[naphtho[1,2-b][1,4]oxathiine-2,4′-piperidine]-5,6-dione, 2-[(oxiran-2-ylmethoxy)methyl]furan and conditions outlined in procedure X. M.p.=143-145° C.; LCMS: 456 [M+H].

Sources & evidence

ORD record
ord-6116c74c172b4792ab55b39643f94b25
Source dataset
uspto-grants-2011_10
Patent number
US08039503B2

Reaction notes

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