2,3-Epoxypropyl 4'-methoxyphenyl ether → HCID 57661919, compound

HRID 1665372Notes

Reaction equation

HRID 1665372 reaction equation
[NH:1]1[CH2:6][CH2:5][C:4]2([O:11][C:10]3[C:12]4[C:17]([C:18](=[O:21])[C:19](=[O:20])[C:9]=3[S:8][CH2:7]2)=[CH:16][CH:15]=[CH:14][CH:13]=4)[CH2:3][CH2:2]1.[CH3:22][O:23][C:24]1[CH:34]=[CH:33][C:27]([O:28][CH2:29][CH:30]2[CH2:32][O:31]2)=[CH:26][CH:25]=1>>[OH:31][CH:30]([CH2:29][O:28][C:27]1[CH:33]=[CH:34][C:24]([O:23][CH3:22])=[CH:25][CH:26]=1)[CH2:32][N:1]1[CH2:2][CH2:3][C:4]2([O:11][C:10]3[C:12]4[C:17]([C:18](=[O:21])[C:19](=[O:20])[C:9]=3[S:8][CH2:7]2)=[CH:16][CH:15]=[CH:14][CH:13]=4)[CH2:5][CH2:6]1

Participants

3

Reactant 2

HCID 166462,3-Epoxypropyl 4'-methoxyphenyl etherHCID 57661820Spiro[naphtho[1,2-b][1,4]oxathiine-2,4'-piperidine]-5,6-dione

Product 1

HCID 57661919HCID 57661919, compound

Procedure

Compound 175 was synthesized using spiro[naphtho[1,2-b][1,4]oxathiine-2,4′-piperidine]-5,6-dione, 2-[(4-methoxyphenoxy)methyl]oxirane and conditions outlined in procedure X. LCMS: 482 [M+H]; Rt=0.99 min.

Sources & evidence

ORD record
ord-3cb716bad8144a26b6ea2365bba56614
Source dataset
uspto-grants-2011_10
Patent number
US08039503B2

Reaction notes

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