2-Methyl-2-phenyloxirane → HCID 57662058, compound

Participants

Reaction Steps

Compound 177 was synthesized using spiro[naphtho[1,2-b][1,4]oxathiine-2,4′-piperidine]-5,6-dione, 2-methyl-2-phenyloxirane and conditions outlined in general procedure X. M.p.=117° C. (dec); 400 MHz 1H NMR (DMSO-d6) δ: 7.88 (d, J=8 Hz, 1H), 7.77 (d, J=4 Hz, 2H), 7.56 (d, J=4 Hz, 1H), 7.49 (d, J=7.2 Hz, 2H), 7.30 (t, J=7.2 Hz, 2H), 7.19 (t, J=7.2 Hz, 1H), 4.84 (bs, 1H), 3.05 (s, 2H), 2.72-2.34 (m, 2H), 1.96-1.83 (m, 4H), 1.80-1.57 (m, 4H), 1.47 (s, 3H). LCMS: 436 [M+H].

Provenance & Evidence