4,6-Dichloropyrimidine → HCID 57662063, compound

Participants

Reaction Steps

Compound 230 was synthesized using spiro[naphtho[1,2-b][1,4]oxathiine-2,4′-piperidine]-5,6-dione, 4,6-dichloropyrimidine and conditions outlined in procedure AA. M.p.=172-174° C.; 400 MHz 1H NMR (DMSO-d6) δ: 8.25 (s, 1H), 7.91-7.86 (m, 2H), 7.76-7.70 (m, 1H), 7.58-7.53 (m, 1H), 7.08 (s, 1H), 3.42-3.33 (m, 4H), 3.10 (s, 2H), 2.09-2.04 (m, 2H), 1.85-1.76 (m, 2H); LCMS: 414 [M+H].

Provenance & Evidence