Sulfur Dioxide → HCID 87253109, compound

Participants

Reaction Steps

1,3-Dibromo-5-chlorobenzene (WAKO, 5.98 g) was dissolved in ether (200 mL), and added with 1.6M n-butyl lithium n-hexane solution (KANTO, 15.2 mL) and liquefied sulfur dioxide (9.7 mL) at −70° C. After being allowed to warm to room temperature, the mixture was stirred for 5 hours. The solvent was distilled off under reduced pressure to obtain the target compound as a crude product. LCMS Method B, retention time 0.83 minutes, (ES−) 254.9

Provenance & Evidence