4-Chlorophenyl Isocyanate → HCID 44514203, compound

HRID 1665461Notes

Reaction equation

HRID 1665461 reaction equation
[N:1]1([C:7]2[N:12]=[C:11]([N:13]3[CH2:18][CH2:17][O:16][CH2:15][CH2:14]3)[N:10]=[C:9]([C:19]3[CH:25]=[CH:24][C:22]([NH2:23])=[CH:21][CH:20]=3)[N:8]=2)[CH2:6][CH2:5][O:4][CH2:3][CH2:2]1.[Cl:26][C:27]1[CH:32]=[CH:31][C:30]([N:33]=[C:34]=[O:35])=[CH:29][CH:28]=1>>[Cl:26][C:27]1[CH:32]=[CH:31][C:30]([NH:33][C:34]([NH:23][C:22]2[CH:24]=[CH:25][C:19]([C:9]3[N:8]=[C:7]([N:1]4[CH2:2][CH2:3][O:4][CH2:5][CH2:6]4)[N:12]=[C:11]([N:13]4[CH2:18][CH2:17][O:16][CH2:15][CH2:14]4)[N:10]=3)=[CH:20][CH:21]=2)=[O:35])=[CH:29][CH:28]=1

Participants

3

Reactant 2

HCID 76934-Chlorophenyl IsocyanateHCID 453790874-(4,6-Dimorpholino-1,3,5-triazin-2-yl)aniline

Product 1

HCID 44514203HCID 44514203, compound

Procedure

Starting from 4-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)aniline (0.140 g 0.40 mmoles) and 4-chlorophenyl isocyanate (94 mg, 0.61 mmoles) the title compound was isolated as a white solid. Yield; 60 mg (30%); (M+H)=496.3

Sources & evidence

ORD record
ord-4ea903670a11476a8c898dddeabb0107
Source dataset
uspto-grants-2011_10
Patent number
US08039469B2

Reaction notes

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