Carbamic acid, 4-pyridinyl-, phenyl ester → HCID 66585542, compound

HRID 1665558Notes

Reaction equation

HRID 1665558 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[N:13]=[C:12]([N:14]3[CH2:19][CH2:18][O:17][CH2:16][CH2:15]3)[N:11]=[C:10]([C:20]3[CH:25]=[CH:24][C:23]([NH:26][C:27]([NH:29][CH3:30])=[O:28])=[CH:22][CH:21]=3)[N:9]=2)=[CH:4][CH:3]=1.[N:31]1[CH:36]=[CH:35][C:34]([NH:37][C:38](=[O:46])OC2C=CC=CC=2)=[CH:33][CH:32]=1>>[CH3:30][NH:29][C:27]([NH:26][C:23]1[CH:22]=[CH:21][C:20]([C:10]2[N:11]=[C:12]([N:14]3[CH2:15][CH2:16][O:17][CH2:18][CH2:19]3)[N:13]=[C:8]([C:5]3[CH:4]=[CH:3][C:2]([NH:1][C:38](=[O:46])[NH:37][C:34]4[CH:33]=[CH:32][N:31]=[CH:36][CH:35]=4)=[CH:7][CH:6]=3)[N:9]=2)=[CH:25][CH:24]=1)=[O:28]

Participants

3

Reactant 2

HCID 11401617Carbamic acid, 4-pyridinyl-, phenyl esterHCID 674385231-(4-(4-(4-Aminophenyl)-6-morpholino-1,3,5-triazin-2-yl)phenyl)-3-methylurea

Product 1

HCID 66585542HCID 66585542, compoundYield 3.9%

Procedure

The title compound was prepared by following the procedure of example 462 step 7 using 1-(4-(4-(4-aminophenyl)-6-morpholino-1,3,5-triazin-2-yl)phenyl)-3-methylurea and phenyl pyridin-4-ylcarbamate. Yield 75 mg, 3.9% yield.

Sources & evidence

ORD record
ord-2483cafb63484d00819fdf1192235377
Source dataset
uspto-grants-2011_10
Patent number
US08039469B2

Reaction notes

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