HuagongsheHuagongshe Chemistry Print Report · For research reference only
Bromine → HCID 10275621, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Bromine | HCID 24408 | — |
| Reactant | Sodium Bicarbonate | HCID 516892 | — |
| Reactant | HCID 58928540 | HCID 58928540 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 10275621 | HCID 10275621 | — |
Reaction Steps
3-{6-[(2,2-Dimethyl-propyl)-methyl-amino]-2-methylamino-pyrimidin-4-ylamino}-4,N-dimethyl-benzamide (33 mg), aq. sat. sodium bicarbonate (0.05 mL) and bromine (14 mg) were stirred in methylene chloride (1 mL) at room temperature for 4 hours. The product (14 mg) was purified with preparative thin layer chromatography. MS (m/z): 449 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08044040B2 |
| Source dataset | uspto-grants-2011_10 |
| ORD ID | ord-491a7b07dc6349dfb80accfd593de0ff |
| Source note | uspto-grants-2011_10 |