HCID 178418361, compound → HCID 178507384, compound

Participants

Reaction Steps

To a solution of (R)-indan-1-yl-(5-nitro-4H-benzo[d][1,3]oxazin-2-yl)-amine (example 1) (1.90 g, 6.1 mmol) in tetrahydrofuran (250 mL) at 23° C. were added three Pasteur pipettes of Raney-Nickel (ready to use 10% suspension in water) and the mixture was vigourously stirred under an atmospheric pressure of hydrogen for 23 h. The catalyst was filtered off, washed with tetrahydrofuran, the solvent was removed in vacuum to give the title compound as a light yellow foam (1.81 g, 99%), MS (ISP) m/e=280.4 [(M+H)+].

Provenance & Evidence