3,5-Difluorobenzenesulfonyl chloride → HCID 178488329, compound

HRID 1666108Notes

Reaction equation

HRID 1666108 reaction equation
[CH3:1][O:2][C:3]1[C:8]2[CH:9]([NH:12][C:13]3[O:14][CH2:15][C:16]4[C:22]([NH2:23])=[CH:21][CH:20]=[CH:19][C:17]=4[N:18]=3)[CH2:10][O:11][C:7]=2[CH:6]=[CH:5][CH:4]=1.[F:24][C:25]1[CH:26]=[C:27]([S:32](Cl)(=[O:34])=[O:33])[CH:28]=[C:29]([F:31])[CH:30]=1>>[F:31][C:29]1[CH:28]=[C:27]([S:32]([NH:23][C:22]2[C:16]3[CH2:15][O:14][C:13]([NH:12][CH:9]4[C:8]5[C:3]([O:2][CH3:1])=[CH:4][CH:5]=[CH:6][C:7]=5[O:11][CH2:10]4)=[N:18][C:17]=3[CH:19]=[CH:20][CH:21]=2)(=[O:33])=[O:34])[CH:26]=[C:25]([F:24])[CH:30]=1

Participants

3

Reactant 2

HCID 27740583,5-Difluorobenzenesulfonyl chlorideHCID 178488328HCID 178488328, compound

Product 1

HCID 178488329HCID 178488329, compound

Procedure

The title compound, MS (ISP) m/e=488.0 [(M+H)+], was prepared from N2-(4-methoxy-2,3-dihydro-benzofuran-3-yl)-4H-benzo[d][1,3]oxazine-2,5-diamine (example 3) and 3,5-difluoro-benzenesulfonyl chloride according to the procedure described for example 5.

Sources & evidence

ORD record
ord-ba622c4680fe410283421047c60452ac
Source dataset
uspto-grants-2011_10
Patent number
US08044047B2

Reaction notes

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