HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Ethyl-3-(3'-dimethylaminopropyl)carbodiimide → HCID 67445007, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Ethyl-3-(3'-dimethylaminopropyl)carbodiimide | HCID 15908 | — |
| Reactant | 1-Hydroxybenzotriazole | HCID 75771 | — |
| Reactant | L-Phenylalanine, N-[(1,1-dimethylethoxy)carbonyl]- | HCID 77857 | — |
| Reactant | Glycine, N-methyl-, methyl ester, hydrochloride (1:1) | HCID 83544 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Solvent | Triethylamine | HCID 8471 | — |
| Product | HCID 67445007 | HCID 67445007 | — |
Reaction Steps
N-(tert-Butoxycarbonyl)-phenylalanine (4.85 g, 15 mmol) was condensed with N-methylglycine methyl ester hydrochloride in DMF in the presence of triethylamine, HOBt and WSC.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08044056B2 |
| Source dataset | uspto-grants-2011_10 |
| ORD ID | ord-85f9e56b455b434daf199a45d64eedf2 |
| Source note | uspto-grants-2011_10 |