HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-Butyl 4-oxopiperidine-1-carboxylate → 4-(3-Benzyloxy-benzylidene)-piperidine-1-carboxylic acid tert-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-Butyl 4-oxopiperidine-1-carboxylate | HCID 735900 | — |
| Reactant | (3-Benzyloxy-benzyl)-phosphonic acid diethyl ester | HCID 10336966 | — |
| Product | 4-(3-Benzyloxy-benzylidene)-piperidine-1-carboxylic acid tert-butyl ester | HCID 66876001 | 56.3% |
Reaction Steps
Following the procedure in Example 1, Step 4, (3-benzyloxy-benzyl)-phosphonic acid diethyl ester (1.0 g, 3.0 mmol, from Step 1) and 4-oxo-piperidine-1-carboxylic acid tert-butyl ester (500 mg, 2.5 mmol) were used to give the title compound (534 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08044052B2 |
| Source dataset | uspto-grants-2011_10 |
| ORD ID | ord-58a9a48a956548e49fa05b7fb71bc084 |
| Source note | uspto-grants-2011_10 |