Ethanol → N-[1-amino-3-[4-[8-(1-hydroxyethyl)imidazo[1,2-a]pyridin-2-yl]phenyl]propan-2-yl]-3-chloro-4-propan-2-yloxybenzamide

HRID 166651Notes

Reaction equation

HRID 166651 reaction equation
[CH3:50][CH2:51][OH:52].[Cl:1][c:2]1[cH:3][c:4]([C:5](=[O:6])[NH:7][CH:8]([CH2:9][N:10]2[C:11](=[O:12])[c:13]3[c:14]([cH:15][cH:16][cH:17][cH:18]3)[C:19]2=[O:20])[CH2:21][c:22]2[cH:23][cH:24][c:25](-[c:28]3[n:29][c:30]4[n:31]([cH:32][cH:33][cH:34][c:35]4[CH:36]([CH3:37])[OH:38])[cH:39]3)[cH:26][cH:27]2)[cH:40][cH:41][c:42]1[O:43][CH:44]([CH3:45])[CH3:46].[NH2:48][NH2:49].[OH2:47]>>[Cl:1][c:2]1[cH:3][c:4]([C:5](=[O:6])[NH:7][CH:8]([CH2:9][NH2:10])[CH2:21][c:22]2[cH:23][cH:24][c:25](-[c:28]3[n:29][c:30]4[n:31]([cH:32][cH:33][cH:34][c:35]4[CH:36]([CH3:37])[OH:38])[cH:39]3)[cH:26][cH:27]2)[cH:40][cH:41][c:42]1[O:43][CH:44]([CH3:45])[CH3:46]

Participants

5

Reactant 4

HCID 702EthanolHCID 962WaterHCID 9321HydrazineHCID 69643544HCID 69643544, compound

Product 1

HCID 76613277N-[1-amino-3-[4-[8-(1-hydroxyethyl)imidazo[1,2-a]pyridin-2-yl]phenyl]propan-2-yl]-3-chloro-4-propan-2-yloxybenzamide

Sources & evidence

ORD record
ord-315cce0ac92542f4b10315411fcab931
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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