4-Cyanophenylboronic acid → 4-(6-Fluoropyridin-3-yl)benzonitrile

HRID 1666543Notes

Reaction equation

HRID 1666543 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5](Br)=[CH:4][N:3]=1.[C:9]([C:11]1[CH:16]=[CH:15][C:14](B(O)O)=[CH:13][CH:12]=1)#[N:10]>>[F:1][C:2]1[CH:7]=[CH:6][C:5]([C:14]2[CH:15]=[CH:16][C:11]([C:9]#[N:10])=[CH:12][CH:13]=2)=[CH:4][N:3]=1

Participants

3

Reactant 2

HCID 27343264-Cyanophenylboronic acidHCID 27831685-Bromo-2-fluoropyridine

Product 1

HCID 231159914-(6-Fluoropyridin-3-yl)benzonitrile

Procedure

According to the same method as in Example 1-2) but using 2-fluoro-5-bromopyridine and 4-cyanophenylboronic acid, the entitled compound was obtained.

Workup

  1. customthe entitled compound was obtained

Sources & evidence

ORD record
ord-3caef534691a4dabba4c04ab820141af
Source dataset
uspto-grants-2011_10
Patent number
US08044070B2

Reaction notes

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