HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 4-Isopropoxy-3-methyl-benzoyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 4-Isopropoxy-3-methylbenzoic acid | HCID 59272935 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | 4-Isopropoxy-3-methyl-benzoyl chloride | HCID 87402609 | — |
Reaction Steps
To a solution of 4-isopropoxy-3-methyl-benzoic acid (1.35 g, 6.95 mmol) in chloroform (20 mL), thionylchloride (2.48 g, 20.9 mmol) is added. The mixture is refluxed for 2 h before the solvents are removed in vacuo to give crude 4-isopropoxy-3-methyl-benzoic acid chloride; LC-MS: tR=1.00 min.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08044076B2 |
| Source dataset | uspto-grants-2011_10 |
| ORD ID | ord-3dd2f232704e4f738e15288e82bcbccd |
| Source note | uspto-grants-2011_10 |