Ethanol → HCID 57970175, compound

HRID 1666668Notes

Reaction equation

HRID 1666668 reaction equation
[Cl:1][C:2]1[N:3]=[C:4](Cl)[C:5]2[S:10][CH:9]=[CH:8][C:6]=2[N:7]=1.[CH2:12]([OH:14])[CH3:13].[OH-].[Na+]>O>[Cl:1][C:2]1[N:3]=[C:4]([O:14][CH2:12][CH3:13])[C:5]2[S:10][CH:9]=[CH:8][C:6]=2[N:7]=1

Participants

5

Reactant 3

HCID 702EthanolHCID 14798Sodium HydroxideHCID 127128322,4-Dichlorothieno[3,2-d]pyrimidine

Product 1

HCID 57970175HCID 57970175, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A mixture of 2,4-dichlorothieno[3,2-d]pyrimidine (0.1 g), ethanol (5 mL), water (0.5 mL) and sodium hydroxide (0.04 g) was stirred at room temperature. The precipitated solids were collected by filtration and washed with diethyl ether to obtain 2-chloro-4-ethoxythieno[3,2-d]pyrimidine (0.07 g).

Workup

  1. filtrationThe precipitated solids were collected by filtration
  2. washwashed with diethyl ether

Sources & evidence

ORD record
ord-ac91d2d061354cdc9a765b23dad97c70
Source dataset
uspto-grants-2011_10
Patent number
US08044068B2

Reaction notes

Loading…