Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Diphenyl Ether | HCID 7583 | — |
| Reactant | HCID 178436969 | HCID 178436969 | — |
| Product | HCID 178436945 | HCID 178436945 | 85.1% |
Reaction Steps
A mixture of 4-ethyl-2-hydroxyquinoline-3-carboxylic acid (0.84 g) and diphenyl ether (2.5 mL) was heated at 250° C. for 2 h with stirring. The mixture was cooled to room temperature and purified by silica gel column chromatography (chloroform/methanol=50:1) to obtain the title compound (0.57 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08044068B2 |
|---|
| Source dataset | uspto-grants-2011_10 |
|---|
| ORD ID | ord-bdbbb5c51b324878841fded9b72b0f60 |
|---|
| Source note | uspto-grants-2011_10 |
|---|
