Bromoacetyl bromide → HCID 67443924, compound

Participants

Reaction Conditions

Reaction Steps

4.9 g (20 mmol) N-(3,4-Dichlorobenzyl)-N-(methyl)propan-1,3-diamine is dissolved in 50 ml dichloromethane. The solution is cooled to −10° C. and at that temperature 2 ml (23 mmol) bromoacetyl bromide in 12 ml dichloromethane is added to it dropwise. The reaction mixture is stirred at −10° C. for 10 minutes and at room temperature for 3 hours. Dichloromethane is poured off, the residue is stirred with 15 ml abs. ethanol, the precipitated crystals are filtered off, washed with ethanol and with ether to obtain 7 g title compound in the form of its hydrogen bromide salt. Mp.: 141° C.

Provenance & Evidence