Potassium Carbonate → 2-(1,3-Benzothiazol-2-yloxy)-N-{3-[(3,4-dichlorobenzyl)(methyl)amino]propyl}-acetamide

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Reaction Steps

0.0756 g (0.5 mmol) 1,3-benzothiazol-2-ol is dissolved in 5 ml dimethylformamide, 0.15 g (1.1 mmol) dry potassium carbonate is added and under stirring at room temperature 0.18 g (0.5 mmol) 2-bromo-N-{3-[(3,4-dichlorobenzyl)(methyl)amino]propyl}acetamide in 2 ml dimethylformamide is added dropwise. Stirring is continued for 24 hours. The reaction mixture is poured onto ice-water mixture, the precipitated crystals are filtered off, washed with water to obtain 0.13 g title compound. Mp: 113-115° C.

Provenance & Evidence