反应详情

温度

5 °C

Amorphous mupirocin calcium (20.00 g, 19.20 mmole) was added into water (20 ml) under stirring. The slurry was stirred for 0.5 hour, and then it was cooled to 5° C. The mupirocin calcium solution was allowed to crystallize for 16 h. The crystal slurry was diluted with 15 ml water, and the crystals were filtered and washed with water (5 ml). The product (17.1 g) was dried at 35° C. for 12 h.

1. stirringThe slurry was stirred for 0.5 hour
2. customto crystallize for 16 h
3. additionThe crystal slurry was diluted with 15 ml water
4. filtrationthe crystals were filtered
5. washwashed with water (5 ml)
6. dry with materialThe product (17.1 g) was dried at 35° C. for 12 h.