Hydrochloric Acid → HCID 21071564, compound

Participants

Reaction Steps

Add a solution of HCl (4.6 mL of 4 M HCl in 1,4-dioxane) dropwise to a solution of 4-phenyltryptamine (3.33 g, 14.09 mmol) in EtOAc/Et2O to give a solid. Collect the solid by filtration and dry overnight in a vacuum oven at room temperature to give the title compound as an off white solid: 1H NMR (300 MHz, d6-DMSO): 2.54 (m, 4H), 6.82 (m, 1H), 7.14 (t, 1H), 7.27 (m, 1H), 7.41 (m, 5H), 7.68 (bs, 2H), 11.28 (bs, 1H); MS (ES+): m/z 237 (M+H)+, 220 (M−NH2)+; (ES−): m/z 235 (M−H)−; Analysis for C16H17ClN2; Calcd.: C, 70.4517; H, 6.2818; N, 10.2696. found: C, 70.26; H, 6.16; N, 10.20.

Provenance & Evidence