Oxalic Acid → HCID 21071597, compound

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Reaction Steps

Add oxalic acid (1.3 eq.) in acetone to a solution of 5-trifluoromethoxytryptamine in acetone. Warm and add Et2O to the cloud point and then placed in the freezer overnight to obtain the title compound as a white crystalline solid: 1H NMR (300 MHz, d6-DMSO): 3.02 (m, 4H), 7.06 (m, 1H), 7.39 (m, 1H), 7.45 (d, 1H), 7.55 (m, 1H), 11.30 (bs, 1H). MS (ES+): m/z 245 (M+H)+, 228 (M−NH2)+; (ES−): m/z 243 (M−H); Analysis for C11H11F3N2O: Calcd.: C, 46.7144; H, 3.9203; N, 8.3809. found: C, 46.55; H, 3.62; N, 8.27.

Provenance & Evidence