HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → 5-Chlorotryptamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 5-Chloro-1H-indole-3-ethylamine monohydrochloride | HCID 2827494 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 5-Chlorotryptamine | HCID 77379 | — |
Reaction Steps
Add 5-chlorotryptamine hydrochloride (15 g, 0.06 mole) water (150 ml), NaOH 1N (75 ml), and dichloromethane (350 mL). Stir the mixture at room temperature for 30 minutes, and separate the phases. Wash the aqueous phase with dichloromethane, combine the organic phases, dry over MgSO4, filter, and evaporate to dryness under vacuum to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08044090B2 |
| Source dataset | uspto-grants-2011_10 |
| ORD ID | ord-a0856b8fc05e4090abb4c08150d35ffa |
| Source note | uspto-grants-2011_10 |