Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
5-Methyl-2-((2-nitrophenyl)amino)-3-thiophenecarbonitrile → 2-(2-Aminoanilino)-5-methylthiophene-3-carbonitrile
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 5-Methyl-2-((2-nitrophenyl)amino)-3-thiophenecarbonitrile | HCID 395460 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Ethyl Acetate | HCID 8857 | — |
| 생성물 | 2-(2-Aminoanilino)-5-methylthiophene-3-carbonitrile | HCID 67445262 | — |
반응 단계
2-(2-Nitroanilino)-5-methylthiophene-3-carbonitrile (100 g) is taken in ethyl acetate (1000 ml). The reaction mixture is then hydrogenated by 5% Pd/C (15 g) at 50-55° C. at 10-12 Kg pressure. The reaction mixture is filtered, and ethyl acetate is distilled off to get the title compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08044196B2 |
| 출처 데이터셋 | uspto-grants-2011_10 |
| ORD ID | ord-302a18ee9fe34f6aa6145ec243e4ccee |
| 출처 메모 | uspto-grants-2011_10 |