反应详情

The title compound was prepared using the procedure described in Example 190 substituting 2-(2-oxo-3,3-diphenylpyrrolidin-1-yl)acetic acid from Example 1C for 2-(3,3-bis(4-fluorophenyl)-2-oxopyrrolidin-1-yl)acetic acid and (Z)-4-chloro-N-hydroxybenzimidamide for (Z)—N-hydroxy-4-(trifluoromethyl)benzimidamide. 1H NMR (300 MHz, CDCl3) δ ppm 7.99-7.91 (m, 2H), 7.49-7.14 (m, 12H), 4.88 (s, 2H), 3.57 (t, J=6.5, 2H), 2.89 (t, J=6.5, 2H); MS (DCI) m/z 430.1 (M+H)+.