N'-Hydroxy-4-(trifluoromethyl)benzene-1-carboximidamide → HCID 67376354, compound

Participants

Reaction Steps

The title compound was prepared using the procedure described in Example 190 substituting 2-(2-oxo-3,3-diphenylpyrrolidin-1-yl)acetic acid from Example 1C for 2-(3,3-bis(4-fluorophenyl)-2-oxopyrrolidin-1-yl)acetic acid and (Z)-4-tert-butyl-N-hydroxybenzimidamide for (Z)—N-hydroxy-4-(trifluoromethyl)benzimidamide. 1H NMR (300 MHz, CDCl3) δ ppm 7.99-7.91 (m, 2H), 7.51-7.46 (m, 2H), 7.42-7.27 (m, 9H), 6.95-6.89 (m, 1H), 4.89 (s, 2H), 3.55 (t, J=6.5, 2H), 2.88 (t, J=6.5, 2H), 1.36 (s, 9H); MS (DCI) m/z 452.2 (M+H)+.

Provenance & Evidence