N'-Hydroxy-4-(trifluoromethyl)benzene-1-carboximidamide → HCID 67359657, compound

Participants

Reaction Steps

The title compound was prepared using the procedure described in Example 190 substituting 2-(2-oxo-3,3-diphenylpyrrolidin-1-yl)acetic acid from Example 1C for 2-(3,3-bis(4-fluorophenyl)-2-oxopyrrolidin-1-yl)acetic acid and (Z)—N-hydroxy-6-(trifluoromethyl)nicotinimidamide for (Z)—N-hydroxy-4-(trifluoromethyl)benzimidamide. 1H NMR (300 MHz, CDCl3) δ ppm 9.33 (s, 1H), 8.43 (dd, J=1.5, 8.2, 1H), 7.80 (dd, J=0.5, 8.2, 1H), 7.44-7.26 (m, 10H), 4.93 (s, 2H), 3.59 (t, J=6.5, 2H), 2.90 (t, J=6.5, 2H); MS (DCI) m/z 465.1 (M+H)+.

Provenance & Evidence