N'-Hydroxy-4-(trifluoromethyl)benzene-1-carboximidamide → HCID 67360667, compound

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Reaction Steps

The title compound was prepared using the procedure described in Example 190 substituting 2-(2-oxo-3,3-diphenylpyrrolidin-1-yl)acetic acid from Example 1C for 2-(3,3-bis(4-fluorophenyl)-2-oxopyrrolidin-1-yl)acetic acid and (Z)—N-hydroxy-4-(trifluoromethyl)nicotinimidamide for (Z)—N-hydroxy-4-(trifluoromethyl)benzimidamide. 1H NMR (300 MHz, CDCl3) δ ppm 9.09 (s, 1H), 8.97 (d, J=5.1, 1H), 7.73 (d, J=5.2, 1H), 7.42-7.18 (m, 10H), 4.95 (s, 2H), 3.59 (t, J=6.5, 2H), 2.89 (t, J=6.5, 2H); MS (DCI) m/z 465.1 (M+H)+.

Provenance & Evidence