N'-Hydroxy-4-(trifluoromethyl)benzene-1-carboximidamide → HCID 45274310, compound

Participants

Reaction Steps

The title compound was prepared using the procedure described in Example 190 substituting 2-(2-oxo-3,3-diphenylpyrrolidin-1-yl)acetic acid from Example 1C for 2-(3,3-bis(4-fluorophenyl)-2-oxopyrrolidin-1-yl)acetic acid and (Z)—N-hydroxypyrazine-2-carboximidamide for (Z)—N-hydroxy-4-(trifluoromethyl)benzimidamide. 1H NMR (300 MHz, DMSO-d6) δ ppm 9.15 (d, J=1.4, 1H), 8.87 (dt, J=2.0, 2.5, 2H), 7.40-7.21 (m, 10H), 5.01 (s, 2H), 3.54 (t, J=6.5, 2H), 2.84 (t, J=6.5, 2H); MS (DCI) m/z 398.3 (M+H)+.

Provenance & Evidence