Sulfuric Acid → Ethyl 7-oxoazepane-4-carboxylate

HRID 1667303Notes

Reaction equation

HRID 1667303 reaction equation
O[N:2]=[C:3]1[CH2:8][CH2:7][CH:6]([C:9]([O:11][CH2:12][CH3:13])=[O:10])[CH2:5][CH2:4]1.S(=O)(=O)(O)[OH:15]>C(O)C>[O:15]=[C:3]1[NH:2][CH2:8][CH2:7][CH:6]([C:9]([O:11][CH2:12][CH3:13])=[O:10])[CH2:5][CH2:4]1

Participants

4

Reactant 2

HCID 1118Sulfuric AcidHCID 11593553Cyclohexanecarboxylic acid, 4-(hydroxyimino)-, ethyl ester

Product 1

HCID 23093698Ethyl 7-oxoazepane-4-carboxylate

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Ethyl 4-(hydroxyimino)cyclohexanecarboxylate was reacted in the presence of conc. sulfuric acid in ethanol to produce ethyl 7-oxoazepane-4-carboxylate.

Sources & evidence

ORD record
ord-16856932143f4c0ba112bc0419913bb8
Source dataset
uspto-grants-2011_10
Patent number
US08044206B2

Reaction notes

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