HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tetrahydrofuran → Tert-butyl 3-formyl-8-azabicyclo(3.2.1)octane-8-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tetrahydrofuran | HCID 8028 | — |
| Reactant | Diisobutylaluminumhydride | HCID 21225700 | — |
| Reactant | tert-Butyl 3-cyano-8-azabicyclo[3.2.1]octane-8-carboxylate | HCID 53487658 | — |
| Product | Tert-butyl 3-formyl-8-azabicyclo(3.2.1)octane-8-carboxylate | HCID 57712307 | — |
Reaction Steps
tert-Butyl 3-cyano-8-azabicyclo[3.2.1]octane-8-carboxylate was reacted in the presence of diisobutyl aluminum hydride in tetrahydrofuran to produce tert-butyl 3-formyl-8-azabicyclo[3.2.1]octane-8-carboxylate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08044206B2 |
| Source dataset | uspto-grants-2011_10 |
| ORD ID | ord-0e237b6c623c4a71989b825c843b5696 |
| Source note | uspto-grants-2011_10 |