HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl chloroformate → HCID 57700391, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl chloroformate | HCID 6586 | — |
| Reactant | HCID 57448197 | HCID 57448197 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | HCID 57700391 | HCID 57700391 | 83% |
Reaction Steps
To 8F (24 mg, 0.09 mmol) in pyridine (15 mL) at 0° C. was added methyl chloroformate (18 μL, 0.24 mmol). After removing the ice bath and stirring at rt 7 h, the reaction was concentrated and purified via preparative HPLC (MeOH/water/TFA) to provide 8G (24 mg, 83%). LC-MS: 361.22 (M+Na)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08044242B2 |
| Source dataset | uspto-grants-2011_10 |
| ORD ID | ord-2d4179186d2047628ea0738f581d5926 |
| Source note | uspto-grants-2011_10 |