Triethylamine → HCID 178466781, compound

Participants

Reaction Steps

To hydroxyamine HCl salt (363 mg, 5.2 mmol) in DMSO (5.0 mL) was added triethyl amine (0.725 mL, 5.2 mmol). After stirring at rt for 10 min, the cloudy solution was filtered directly into a round-bottom flask containing 9A (482 mg, 1.3 mmol). The mixture was stirred at 60° C. for 18 h before it was diluted with ethyl acetate and washed with 5% NaHCO3/brine. The organic extract was dried over Na2SO4 and concentrated to give 9B as a white solid. LC-MS 403 (M+H)+.

Provenance & Evidence