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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1667842Generated: November 3, 2026

Methanol → HCID 57441041, compound

https://huagongshe.com/reaction/1667842

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethanolHCID 887—
ReactantTetrahydrofuranHCID 8028—
ReactantLithium hydroxide, monohydrateHCID 168937—
ReactantHCID 57441040HCID 57441040—
SolventWaterHCID 962—
ProductHCID 57441041HCID 5744104190.5%

Reaction Steps

Using methyl 3-(1-cyanocyclohexyl)benzoate (1.3 g, 5.3 mmol), lithium hydroxide-monohydrate (0.52 g, 13 mmol), tetrahydrofuran (18 mL), methanol (6.0 mL) and water (6.0 mL) as starting materials and in the same manner as in Reference Example 37, the title compound (1.1 g, 88%) was obtained as a white powder.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08044049B2
Source datasetuspto-grants-2011_10
ORD IDord-eefba881e0124cb29fde5ae47220a6d2
Source noteuspto-grants-2011_10