HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → N-[6-(3-aminophenoxy)imidazo[1,2-b]pyridazin-2-yl]-2-methylpropanamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 3-Aminophenol | HCID 11568 | — |
| Reactant | N-(6-iodoimidazo[1,2-b]pyridazin-2-yl)-2-methylpropanamide | HCID 57441028 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | N-[6-(3-aminophenoxy)imidazo[1,2-b]pyridazin-2-yl]-2-methylpropanamide | HCID 57505515 | 47% |
Reaction Steps
Using N-(6-iodoimidazo[1,2-b]pyridazin-2-yl)-2-methylpropanamide (0.60 g, 1.82 mmol), N,N-dimethylformamide (6.0 mL), potassium carbonate (502 mg, 3.63 mmol) and 3-aminophenol (278 mg, 2.54 mmol) as starting materials and in the same manner as in Example 91, the title compound (0.26 g, 47%) was obtained as a dark brown powder.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08044049B2 |
| Source dataset | uspto-grants-2011_10 |
| ORD ID | ord-e26b983c37d143549dad510fa44235f9 |
| Source note | uspto-grants-2011_10 |