HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → HCID 57505623, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | N-(6-iodoimidazo[1,2-b]pyridazin-2-yl)cyclopropanecarboxamide | HCID 57386058 | — |
| Reactant | HCID 57505437 | HCID 57505437 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 57505623 | HCID 57505623 | 61.3% |
Reaction Steps
In the same manner as in Example 257 and using N-(6-iodoimidazo[1,2-b]pyridazin-2-yl)cyclopropanecarboxamide (210 mg, 0.65 mmol), 4-chloro-3-{[(1,3-dimethyl-1H-pyrazol-5-yl)methyl]amino}phenol (240 mg, 0.97 mmol), potassium carbonate (220 mg, 1.6 mmol) and N,N-dimethylformamide (1.5 mL) as starting materials, the title compound (180 mg, 61%) was obtained as a brown solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08044049B2 |
| Source dataset | uspto-grants-2011_10 |
| ORD ID | ord-3fcbcb77142c48c089f0d5db326867d2 |
| Source note | uspto-grants-2011_10 |