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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1668263Generated: October 30, 2026

Hydrazine → Ethyl 3-oxo-3H-pyrazole-5-carboxylate

https://huagongshe.com/reaction/1668263

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrazineHCID 9321—
ReactantDiethyl oxalacetateHCID 66951—
Reactant2,5-Dihydro-5-oxo-1H-pyrazole-3-carboxylic acidHCID 3084676—
ProductEthyl 3-oxo-3H-pyrazole-5-carboxylateHCID 19858287—

Reaction Steps

3-carboxy-1H-pyrazol-5-one, for example, can thus be prepared by reacting diethyl oxalacetate with hydrazine to yield 3-(carboethoxy)-pyrazol-5-one, followed by refluxing in aqueous HCl solution to hydrolyze the ethyl ester.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07988740B2
Source datasetuspto-grants-2011_08
ORD IDord-0de7c4e7f1254c798623acd97ef71758
Source noteuspto-grants-2011_08