Methanol → HCID 59239832, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of the compound (0.49 g) obtained in Example 12, potassium carbonate (0.39 g), water (4 ml), methanol (8 ml) and tetrahydrofuran (8 ml) was stirred at 60° C. for 3 hr. The reaction mixture was diluted with water and extracted with ethyl acetate. The organic layer was washed with saturated brine, dried over magnesium sulfate, and concentrated under reduced pressure. The residue was crystallized from ethyl acetate to give the title compound (79 mg) as a colorless powder.

Provenance & Evidence