Hydrogen chloride-ethyl acetate → HCID 67360608, compound

HRID 1668407Notes

Reaction equation

HRID 1668407 reaction equation
C(OCC)(=O)C.[ClH:7].[Cl:8][C:9]1[CH:14]=[CH:13][C:12]([C:15]2[S:23][C:22]3[C:21](=[O:24])[N:20]([CH2:25][CH2:26][C:27]4[CH:47]=[CH:46][C:30]([CH2:31][N:32]5[CH2:37][CH2:36][N:35](C(OC(C)(C)C)=O)[CH2:34][C:33]5=[O:45])=[CH:29][CH:28]=4)[CH:19]=[N:18][C:17]=3[CH:16]=2)=[CH:11][CH:10]=1>>[ClH:8].[ClH:7].[Cl:8][C:9]1[CH:10]=[CH:11][C:12]([C:15]2[S:23][C:22]3[C:21](=[O:24])[N:20]([CH2:25][CH2:26][C:27]4[CH:28]=[CH:29][C:30]([CH2:31][N:32]5[CH2:37][CH2:36][NH:35][CH2:34][C:33]5=[O:45])=[CH:46][CH:47]=4)[CH:19]=[N:18][C:17]=3[CH:16]=2)=[CH:13][CH:14]=1

Participants

3

Reactant 2

HCID 21866389Hydrogen chloride-ethyl acetateHCID 59239863HCID 59239863, compound

Product 1

HCID 67360608HCID 67360608, compound

Procedure

4N Hydrogen chloride-ethyl acetate solution (6 ml) was added to the compound (75 mg) obtained in Example 37, and the mixture was stirred at room temperature for 1 hr. The solvent was evaporated under reduced pressure, and the residue was washed with ethyl acetate to give the title compound (72 mg) as a colorless powder.

Workup

  1. customThe solvent was evaporated under reduced pressure
  2. washthe residue was washed with ethyl acetate

Sources & evidence

ORD record
ord-c92b98bbd2c84be1a80054b114e14776
Source dataset
uspto-grants-2011_08
Patent number
US07989445B2

Reaction notes

Loading…