Acetyl chloride → HCID 59239847, compound

Participants

Reaction Steps

A mixture of the compound (30 mg) obtained in Example 38, acetyl chloride (4.7 mg), triethylamine (19 mg) and tetrahydrofuran (2 ml) was stirred at room temperature for 1 hr. The reaction mixture was diluted with ethyl acetate, washed with water and saturated brine, dried over anhydrous sodium sulfate, and concentrated under reduced pressure. The residue was recrystallized from ethyl acetate-hexane (1:1, volume ratio) to give the title compound (20 mg) as a colorless powder.

Provenance & Evidence