HuagongsheHuagongshe Chemistry Print Report · For research reference only
Toluene → HCID 15985611, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Toluene | HCID 1140 | — |
| Reactant | HCID 66995328 | HCID 66995328 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 15985611 | HCID 15985611 | — |
Reaction Steps
Product 11I is reconstituted in 20% trifluoroacetatic acid in dichloromethane (50 mL). Stirring until reaction complete by HPLC. Toluene is added and concentrated to an amber oil. The product is dissolved in dichloromethane and washed with saturated bicarb followed by drying over anhydrous magnesium sulfate, filtering and concentrating. HPLC purification to yield 12. LCMS characterization ES+413.1 (m+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07989441B2 |
| Source dataset | uspto-grants-2011_08 |
| ORD ID | ord-31b451374fec4b13ac2003712bcea3bb |
| Source note | uspto-grants-2011_08 |