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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1668566Generated: October 31, 2026

Butyryl chloride → 2-Propyl-6,7,8,9-tetrahydro-5H-[1,3]oxazolo[4,5-h][3]benzazepine

https://huagongshe.com/reaction/1668566

Reaction equation

Participants

RoleNameHCIDCharge
ReactantButyryl chlorideHCID 8855—
Reactant1,1-Dimethylethyl 7-amino-8-hydroxy-1,2,4,5-tetrahydro-3H-3-benzazepine-3-carboxylateHCID 59150472—
Product2-Propyl-6,7,8,9-tetrahydro-5H-[1,3]oxazolo[4,5-h][3]benzazepineHCID 59150503—

Reaction Steps

The title compound was prepared as described in General Procedure 2 from 1,1-dimethylethyl 7-amino-8-hydroxy-1,2,4,5-tetrahydro-3H-3-benzazepine-3-carboxylate and butyryl chloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07989444B2
Source datasetuspto-grants-2011_08
ORD IDord-375a8b589f3a4aa6b943d5ab53c24507
Source noteuspto-grants-2011_08