5-(5-[(3-chloropropyl)thio]-4-methyl-4H-1,2,4-triazol-3-yl)-2-methylquinoline → HCID 67357756, compound

HRID 1668604Notes

Reaction equation

HRID 1668604 reaction equation
[O:1]1[C:5]2=[CH:6][C:7]3[CH2:13][CH2:12][NH:11][CH2:10][CH2:9][C:8]=3[CH:14]=[C:4]2[N:3]=[CH:2]1.[Cl:15][CH2:16][CH2:17][CH2:18][S:19][C:20]1[N:21]([CH3:36])[C:22]([C:25]2[CH:34]=[CH:33][CH:32]=[C:31]3[C:26]=2[CH:27]=[CH:28][C:29]([CH3:35])=[N:30]3)=[N:23][N:24]=1>>[ClH:15].[CH3:36][N:21]1[C:22]([C:25]2[CH:34]=[CH:33][CH:32]=[C:31]3[C:26]=2[CH:27]=[CH:28][C:29]([CH3:35])=[N:30]3)=[N:23][N:24]=[C:20]1[S:19][CH2:18][CH2:17][CH2:16][N:11]1[CH2:10][CH2:9][C:8]2[CH:14]=[C:4]3[N:3]=[CH:2][O:1][C:5]3=[CH:6][C:7]=2[CH2:13][CH2:12]1

Participants

3

Reactant 2

HCID 251050505-(5-[(3-chloropropyl)thio]-4-methyl-4H-1,2,4-triazol-3-yl)-2-methylquinolineHCID 59150475HCID 59150475, compound

Product 1

HCID 67357756HCID 67357756, compound

Procedure

The title compound was prepared in analogy to General Procedure 1 from 6,7,8,9-tetrahydro-5H-[1,3]oxazolo[4,5-h][3]benzazepine (0.10 mmol) and 5-{5-[(3-chloropropyl)thio]-4-methyl-4H-1,2,4-triazol-3-yl}-2-methylquinoline and was obtained as a colourless slightly hygroscopic solid (15 μmol)

Sources & evidence

ORD record
ord-33c91e941e224428a9049ac3b09aa258
Source dataset
uspto-grants-2011_08
Patent number
US07989444B2

Reaction notes

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