3-[(3-Chloropropyl)thio]-4-methyl-5-[4-(trifluoromethyl)phenyl]-4H-1,2,4-triazole → 3-methyl-7-[3-({4-methyl-5-[4-(trifluoromethyl)phenyl]-4H-1,2,4-triazol-3-yl}thio)propyl]-6,7,8,9-tetrahydro-5H-isoxazolo[4,5-h][3]benzazepine hydrochloride

Participants

Reaction Steps

The title compound was prepared in analogy to General Procedure 1 from 3-methyl-6,7,8,9-tetrahydro-5H-isoxazolo[4,5-h][3]benzazepine (0.12 mmol) and 3-[(3-chloropropyl)thio]-4-methyl-5-[4-(trifluoromethyl)phenyl]-4H-1,2,4-triazole (0.14 mmol) and was obtained as a faint yellow slightly hygroscopic solid (0.01 mmol).

Provenance & Evidence