4-methyl-5-(2-methyl-5-quinolinyl)-4H-1,2,4-triazole-3-thiol → HCID 67359218, compound

HRID 1668617Notes

Reaction equation

HRID 1668617 reaction equation
[Cl:1][CH2:2][CH2:3][N:4]1[CH2:10][CH2:9][C:8]2[CH:11]=[C:12]3[N:17]=[C:16]([CH3:18])[O:15][C:13]3=[CH:14][C:7]=2[CH2:6][CH2:5]1.[CH3:19][N:20]1[C:24]([C:25]2[CH:34]=[CH:33][CH:32]=[C:31]3[C:26]=2[CH:27]=[CH:28][C:29]([CH3:35])=[N:30]3)=[N:23][NH:22][C:21]1=[S:36]>>[ClH:1].[CH3:18][C:16]1[O:15][C:13]2[C:12]([N:17]=1)=[CH:11][C:8]1[CH2:9][CH2:10][N:4]([CH2:3][CH2:2][S:36][C:21]3[N:20]([CH3:19])[C:24]([C:25]4[CH:34]=[CH:33][CH:32]=[C:31]5[C:26]=4[CH:27]=[CH:28][C:29]([CH3:35])=[N:30]5)=[N:23][N:22]=3)[CH2:5][CH2:6][C:7]=1[CH:14]=2

Participants

3

Reactant 2

HCID 446275704-methyl-5-(2-methyl-5-quinolinyl)-4H-1,2,4-triazole-3-thiolHCID 59150497HCID 59150497, compound

Product 1

HCID 67359218HCID 67359218, compound

Procedure

The title compound was prepared in analogy to General Procedure 1 from 7-(2-chloroethyl)-2-methyl-6,7,8,9-tetrahydro-5H-[1,3]oxazolo[4,5-h][3]benzazepine (0.11 mmol) and 4-methyl-5-(2-methyl-5-quinolinyl)-2,4-dihydro-3H-1,2,4-triazole-3-thione (0.11 mmol) and was obtained in 40 mg yield.

Workup

  1. customwas obtained in 40 mg
  2. customyield

Sources & evidence

ORD record
ord-4010e2f8d85f482fb335aa8e84e3e368
Source dataset
uspto-grants-2011_08
Patent number
US07989444B2

Reaction notes

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